Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia
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چکیده
منابع مشابه
Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia.
Primary cilia are solitary, microtubulebased organelles that serve as signaling hubs for the Hedgehog (Hh) pathway, which regulates embryonic development and adult tissue homeostasis. While protein localization studies have suggested that the dynamic trafficking of Hh components at cilia plays an important role, the molecular basis of Hh signal transduction at cilia is not well understood. In a...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2014
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201489294